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In contrast to the -adrenergic neurotransmitters that enhance pituitary GH activity by stimulating and inhibiting GHRH and SRIF, respectively, -adrenergic systems have the opposite effect, thereby providing CNS control over GH homeostasis

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As repeatedly emphasized in NephJC discussions, the signal remained consistent even as study populations broadened (should we just add them to the water supply?) Flozination became shorthand for a mindset: trust outcomes over labels