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The initial screening based on binding score cut off of -7.0 kcal/mol delivered top 10 hits which were subjected to pharmacokinetic studies

Standard dosages range from 0.25 mg to 2.4 mg for weekly injections, depending on the prescription

(8.3) Geriatric Patients: Higher incidence of adverse reactions related to volume depletion and reduced renal function

[6] [1] These symptoms were generally mild to moderate in severity and typically occurred during dose escalation phases

10.1210/en.2005-1610 5 AntonelliA.FerrariS

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