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Upregulation of matrix metalloproteinase-9/2 in the wounded tissue, dorsal root ganglia, and spinal cord is involved in the development of postoperative pain
STAT3 is responsible for mediating cellular responses to growth factors, interleukins, etc., and plays a part in cellular processes like apoptosis 42 , while also acting as a regulator of inflammatory responses 43
Dellgren, Govind Persad, and Ezekiel J
This can vary based on technique and individual sensitivity
& Yuan, S
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