By recharging each other, they ensure that your bodys antioxidant defense system never runs out of fuel
(PMID: 34827486) and the broader systematic review by Ho and Nation (PMID: 29733881) provide some supporting evidence from outside the affected research group
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The Cochrane Collaboration (2008)
What to avoid when taking glutathione To get the most from glutathione, it helps to reduce the things that deplete it: Alcohol heavily depletes glutathione and burdens the liver Smoking a major source of oxidative stress Excess processed and fried food increases free-radical load Poor sleep and chronic stress both lower natural production There aren't many strict "don't combine with X" rules for healthy adults, but if you take regular medication, have a medical condition, or are pregnant or breastfeeding, talk to your doctor first (see disclaimer below)