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Dose Titration Strategy to Reduce All GI Effects Slower titration is the most evidence-supported method for reducing GI side effects without sacrificing efficacy

BJU Int, 117: 677-685

In addition to diabetes treatment, the function of metformin also can be anti-aging, antiviral, and anti-inflammatory

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Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue

The lowest concentrations in plasmatic UAc and the highest concentrations in plasmatic TC and LDL were observed in treatments where no L-carnitine was added (T2 and T3), whereas the highest concentrations in plasmatic UAc and the lowest concentrations in plasmatic TC and LDL were seen in the groups supplemented with 150 mg/kg L-carnitine (T7, T8 and T9)