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Isoloquiritigenin led to apoptosis and autophagy-mediated cell death by decreasing cyclin D1 expression as increasing the number of cells in the sub-G1 phase, which inhibited the proliferation of breast cancer cells (141)

How Biologic Therapies Support Healing These therapies can: Reduce inflammation more quickly and more thoroughly Support regeneration of cartilage, tendon, ligament, or other tissues Promote long-term structural repair rather than temporary symptom relief Improve joint stability and tissue quality over time Instead of simply signaling the body to repair itself, biologics may provide both the signals and the building blocks needed for deeper regeneration