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mTOR : Activacin de la maquinaria de sntesis proteica Efectos Biolgicos | Efecto | Mecanismo | Tejido Principal | |--------|-----------|------------------| | Sntesis proteica | mTOR/p70S6K | Msculo esqueltico | | Proliferacin | MAPK/ERK | Mltiples | | Anti-apoptosis | PI3K/Akt/Bad | Mltiples | | Captacin de glucosa | GLUT4 | Msculo, adiposo | | Diferenciacin | Myogenin/MyoD | Clulas satlite | El Eje GH/IGF-1 Para entender IGF-1 LR3, es necesario contextualizar el eje somatotrpico: 1