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doi: 10.1007/s13181-018-0653-9 [PubMed] 29605069 Bunchorntavakul C, Reddy KR

Glutathione-S-transferases M1 (GSTM1) and GSTT1 genotype, smoking, consumption of alcohol and tea and risk of esophageal and stomach cancers: a case-control study of a high-incidence area in Jiangsu Province, China

Lancet 401 (10385), 13711380

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Excessive activation of Nrf2 upregulate antioxidant enzymes necessary for the synthesis of GSH, which counterbalance increased ROS formation and thereby does not enable ROS-mediated cell death