Safety in TRIUMPH-1 The safety profile was consistent with incretin-class therapies: Most common AEs (12 mg dose): - Nausea: 42.4% - Diarrhea: 32.0% - Constipation: 26.1% - Vomiting: 25.3% Dysesthesia (a sensory disturbance tingling, numbness) and urinary tract infections were reported in approximately 10% of patients on the highest doses, but were generally mild to moderate and mostly resolved during treatment
These findings suggest a crucial role of CPT1A-induced ferroptosis resistance in LCSCs to evade attack by cytotoxic T cells
Wespers findings solidify its role as a vital tool in assisting healthcare providers to diagnose and manage obesity-related sleep apnea, particularly for patients undergoing GLP-1 therapy
Athletes: High bone turnover, indoor training, and higher sweat losses may increase both D3 and K2 requirements
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Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, et al