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JAMA 322 , 12941304 (2019)

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Monitoring focuses on glucose trends, kidney/liver context, lipids, and symptoms tied to reduced intake or GI effects

On the other hand, chronic alcohol abuse in combination with malnutrition (low hepatic GSH levels), longer duration of supratherapeutic APAP consumption, and older age with potential co-morbidities can trigger hepatotoxicity [179]