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For Skyrizi, the company expects to see data from Phase III studies in psoriatic arthritis later this year, and in Crohns disease, at the end of 2020 or early next year

Although the combined use of metformin and simvastatin alters energy metabolism, leading to an increase in SREBP2 levels, the elevated SREBP2 precursor is likely to stem from disrupted lipid metabolism

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