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Within approved trials, preparation is carried out solely by trained pharmacy or clinical staff under strictly controlled aseptic conditions, using validated protocols specific to each trial formulation

For example, one study found that Lexapro (escitalopram), Paxil (paroxetine), and Cymbalta (duloxetine) were associated with a higher risk of weight gain than some other antidepressants

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Digenio AG, Mancuso JP, Gerber RA, Dvorak RV