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In animal models of PD, GLP-1 receptor agonists reduced the activation of glia as well [150, 156, 157, 172]

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We need high quality, prospective, randomised controlled trials to definitively make that recommendation. REUTERS

Nausea, diarrhea, vomiting, constipation, abdominal pain, decreased appetite, and fatigue occurring in 5% of participants in clinical trials, mostly mild-to-moderate and peaking during dose escalation

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Convenience drives research into transdermal patches, sublingual formulations, and improved oral delivery systems