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The de novo synthesis of serine from 3-PG occurs in a chain of consecutive enzymatic reactions catalyzed by phosphoglycerate dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1) and phosphoserine phosphatase (PSPH)

Homocysteine, a new cardiovascular risk factor, is also a powerful uremic toxin

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Only participants randomized to receive semaglutide at doses of 0.5 mg or 1.0 mg once weekly were included in this analysis

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