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PMID: 23621168

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4.1 Nrf2 The redox-sensitive transcriptional regulator nuclear factor E2-related factor-2 (Nrf2) plays a crucial role in conferring resistance against intracellular ROS by activating the transcription of antioxidant genes to modulate cellular redox homeostasis (73)

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This review examines cancer-specific fungal communities, the impact of fungal microbiome on cancer cell progression, similarities between fungal differentiation and cells turning cancerous at biochemical and molecular levels, including the overlaps in signal transduction pathways between fungi and cancer

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