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Here the Intrinsic Factor binds to the B12 and the "B12/IF Complex" enters the cells on the wall of the Ileum after binding to receptors on the surface of the Ileal cells, allowing it to enter the blood stream

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You are at risk for B12 deficiency if you: Are a vegetarian Are a vegan Have chronic gastritis Have had previous surgery on your stomach Have any chronic bowel conditions, such as Chrons disease or colitis You take certain medications, such as proton pump inhibitors (PPI's) - a medicine sometimes used to treat heartburn and indigestion What are the signs and symptoms associated with a B12 deficiency

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(September 2015)