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[DOI] [PubMed] [Google Scholar] 93.Ostermeyer AG, Paci JM, Zeng Y, Lublin DM, Munro S, Brown DA
BPC-157 and TB-500 operate through fundamentally different molecular mechanisms: BPC-157 modulates the nitric oxide system and upregulates growth factors including EGF, VEGF, and FGF-2 to promote cytoprotection and angiogenesis, while TB-500 sequesters G-actin monomers to regulate actin polymerization, cytoskeletal dynamics, and cell migration
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However, to our knowledge there have been no studies of growth factors tested in animal models with naturally occurring IVD degeneration